Trans-Anethole

Synonyms: 4-Propenylanisole

Trans-anethole (4-Propenylanisole) is a phenylpropene derivative found in many essential oils, including anise oil. It has neuromodulatory, anxiolytic, antioxidative, antifungal, anti-inflammatory, and immunomodulatory activities.

Trans-Anethole Chemical Structure

Trans-Anethole Chemical Structure

CAS No. 4180-23-8

Purity & Quality Control

Batch: S399001 DMSO]29 mg/mL]false]]]false]]]false Purity: 99.96%
99.96

Trans-Anethole Related Products

Biological Activity

Description Trans-anethole (4-Propenylanisole) is a phenylpropene derivative found in many essential oils, including anise oil. It has neuromodulatory, anxiolytic, antioxidative, antifungal, anti-inflammatory, and immunomodulatory activities.
In vitro
In vitro Trans-anethole markedly reduces neuronal cell death induced by oxygen-glucose deprivation/reoxygenation (OGD/R), an in vitro model of cerebral ischemia. Thus, trans-anethole is a neuroprotective agent to ameliorate ischemic neuronal damage[1].
In Vivo
In vivo Pretreatment with trans-anethole can lead to moderate protective effects against in vivo genotoxicity[2].
Animal Research Animal Models Male swiss albino mice
Dosages 40-400 mg/kg
Administration by gavage

Chemical Information & Solubility

Molecular Weight 148.20 Formula

C10H12O

CAS No. 4180-23-8 SDF --
Density 0.988 g/mL
Smiles CC=CC1=CC=C(C=C1)OC
Storage (From the date of receipt) 2 years -20°C liquid

In vitro
Batch:

DMSO : 29 mg/mL ( (195.68 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
Batch:

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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